Case Reports: Tumor Detection by Diffusion-Weighted MRI and ADC-Mapping with Correlation to PET/CT Results

Early and accurate estimation of metastatic spread is essential for a patient-adapted, efficient therapy regime. In this context, whole-body and multi-step MRI have already helped to improve the diagnostic accuracy of staging examinations. As a further step, it is known that cancer is also often characterized by higher cellularity and therefore restriction of water diffusion. Diffusion-weighted imaging (DWI) with high b-values has therefore been applied to image metastases in order to help improve the diagnostic accuracy of MRI. The working-group of Schlemmer et al., Department of Radiology, University of Tuebingen, Germany, have compared the findings with results of 18F-FDG PET/CT exams.

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