Rapid Body Composition Measurements Reveal Detailed Metabolic Changes in Large Scale Population Studies

Body composition measurements, such as adipose tissue compartments, muscle volumes, and muscle tissue composition are increasingly important in research and clinical context. This article introduces a protocol for robust neck-to-knee Dixon VIBE-based fat and water images at 3T. [...]

Imaging of the Pancreas: Technique and Clinical Applications

The article describes the experiences with REMyDI (Rapid Estimation of Myelin for Diagnostic Imaging), a method of myelin detection in the brain, using a scan time of approximately 6 minutes. [...]

To Add Myelin Detection to Your Neuro Protocol Without Additional Scan Time

The article describes the experiences with REMyDI (Rapid Estimation of Myelin for Diagnostic Imaging), a method of myelin detection in the brain, using a scan time of approximately 6 minutes. [...]

Optimizing Fiducial Markers for MRI-based Radiotherapy

Fiducial markers need to fulfill many, sometimes competing, criteria when used for MRI based radiotherapy treatment planning. This article covers the development and optimization of markers. [...]

Performing Gynecologic Brachytherapy in the Medical Innovation Technical Expert Center

Houda Bahig et al. describe their intensity modulated radiotherapy planning workflow with MRI for locally advanced head-and-neck cancer (HNC) and discuss the current role of MRI in HNC treatment planning. [...]

Evaluation of Transient Motion During Gadoxetic Acid–Enhanced Multiphasic Liver Magnetic Resonance Imaging Using Free-Breathing Golden-Angle Radial Sparse Parallel Magnetic Resonance Imaging

Transient motion developed in 40% of patients shortly after gadoxetic acid administration, and gated free-breathing T1WI using GRASP was able to consistently provide acceptable arterial phase imaging in patients who exhibited transient motion. [...]

MRI in Head and Neck Radiotherapy Planning

Houda Bahig et al. describe their intensity modulated radiotherapy planning workflow with MRI for locally advanced head-and-neck cancer (HNC) and discuss the current role of MRI in HNC treatment planning. [...]

Assessing Brain Volumes Using MorphoBox Prototype

This review focuses on 8 critical questions regarding gadolinium deposition in the brain and body, with the answers and discussion therein important for future regulatory decisions and clinical practice. [...]

High-resolution, Anatomically-accurate Diffusion-weighted Imaging of Orbital and Sinonasal Lesions with RESOLVE

This paper reviews four recently published studies where RESOLVE was shown to be clinically effective in the diffusion-weighted imaging of sinonasal and optic pathologies. It also demonstrates the clinical value that RESOLVE brings to the detection and characterization of the diseases in these regions. [...]

The Assessment of Endolymphatic Hydrops with High-resolution 3D Real Inversion Recovery and 3D Fluid Attenuated Inversion Recovery Sequences

Endolymphatic hydrops in patients with Meniere’s disease can be visualized using MR imaging. This article compares 3D SPACE FLAIR and 3D real IR in terms of the imaging results. [...]

Transurethral MR-Thermometry Guided Ultrasound Ablation of the Prostate – The Heidelberg Experience During Phase I of the TULSA-PRO Device Trial

This article describes a novel, MRI-guided, minimally-invasive method to safely ablate target benign and malignant prostate tissue with millimeter accuracy and precision. Real-time MR thermometry performed during transurethral ultrasound delivery enables active feedback control of the thermal volume, with high success in the ablation of the target tissue. [...]

syngo.MR Neuro 3D: Your All-In-One Post Processing, Visualization and Reporting Engine for BOLD Functional and Diffusion Tensor MR Imaging Datasets

Within this article, we have described our preferred workflow and steps for the processing and analysis of BOLD fMRI and DTI data. [...]

Further Customization of Dot Engines: AutoCoverage

This article details the steps to adjust and manipulate the coverage in the slice direction by using AutoCoverage available in many Dot AddIns. AutoCoverage is a powerful option, and will ensure that the complete anatomy will be covered in the underlying protocol. [...]

Biograph mMR System and Clincal Use Today

This article describes the latest technical and clinical developments for the Biograph mMR. Seminal publications in the field of neurology, cardiology, and oncology are discussed. [...]

Pictorial Essay: Pulmonary Imaging for Children

Especially in children with oncologic diseases that can be treated curatively, MRI can be used for the thoracic staging of the axillary, hilar, and mediastinal lymph nodes and to assess pulmonary metastases. The pictorial essay presents 5 cases. [...]

Multiparametric MRI at 3 Tesla for Prediction of Treatment Response in Rectal Cancer

The article describes the successful integration of a multiparametric MRI technique to monitor response to treatment in patients with rectal cancer. A voxel-by-voxel multiparametric analysis strategy has been adopted and early results show this is important in quantitatively assessing heterogeneity within the entire tumor region, and the changes in response to CRT in rectal cancer. [...]

Critical Questions Regarding Gadolinium Deposition in the Brain and Body After Injections of the Gadolinium-Based Contrast Agents, Safety, and Clinical Recommendations in Consideration of the EMA’s Pharmacovigilance and Risk Assessment Committee Recommendation for Suspension of the Marketing Authorizations for 4 Linear Agents

This review focuses on 8 critical questions regarding gadolinium deposition in the brain and body, with the answers and discussion therein important for future regulatory decisions and clinical practice. [...]

Safety of the Gadolinium-Based Contrast Agents for Magnetic Resonance Imaging, Focusing in Part on Their Accumulation in the Brain and Especially the Dentate Nucleus

This review discusses first the background in terms of development of these agents and safety discussions therein, proceeds to a discussion of NSF and gadolinium deposition in the brain, and concludes with a discussion of the predictable future – specifically reassessment of the use of the linear GBCAs or a subset thereof. [...]

The Potential Role of Ultrashort Echo Time Sequences in MRI Guided Radiotherapy

This work shows the potential of ultra-short TE sequences to play an important role in MR guided Radiotherapy. Acquiring signal intensity at vastly reduced echo time opens up new imaging contrasts and many possibilities. [...]

Overview of Magnetic Resonance Fingerprinting

This overview of Magnetic Resonance Fingerprinting describes the basic concepts of MRF and illustrates some clinical applications. [...]

New ‘ADC & b-value’ Tool in syngo.via

This article describes the feature ‘ADC & computed b-value’ available on Siemens’ syngo.via VB10. This new tool provides an increased degree of freedom in the choice of the b-value for disease detection and characterization. [...]

MR-Guided Biopsies of the Prostate in Supine Patient Position

The article shows that targeted biopsies of the prostate under direct MRI-guidance are a reasonable complement to ultrasound biopsy techniques. The presented cases show that exact targeting of the most suspicious portion of a tumor is crucial for correct classification and consequently best therapy decisions. Especially in case of relatively small lesions, direct MR-guidance has clear advantages over fusion techniques. [...]

Pediatric Pathologies that have Leukocoria as Presenting Sign: the Podium

The article features the clinical and imaging signs and differential diagnosis of Retinoblastoma, persistent fetal vasculature and Coats’ disease. View/Download [...]

Application of Extracellular Gadolinium-based MRI Contrast Agents and the Risk of Nephrogenic Systemic Fibrosis

Presented is a review of nephrogenic systemic fibrosis and how this influences daily practice (in contrast enhanced magnetic resonance imaging), with specific clinical recommendations. Download PPTX-zip [...]

Accelerating Clinical MRI in the 21st Century

The established class of intravenous contrast media for magnetic resonance imaging is the gadolinium chelates, more generally referred to as the gadolinium-based contrast agents (GBCAs). [...]

Magnetic Resonance Imaging and Computed Tomography of the Brain – 50 Years of Innovation, With a Focus on the Future

The established class of intravenous contrast media for magnetic resonance imaging is the gadolinium chelates, more generally referred to as the gadolinium-based contrast agents (GBCAs). [...]

Safety of the Gadolinium-Based Contrast Agents for Magnetic Resonance Imaging, Focusing in Part on Their Accumulation in the Brain and Especially the Dentate Nucleus

The established class of intravenous contrast media for magnetic resonance imaging is the gadolinium chelates, more generally referred to as the gadolinium-based contrast agents (GBCAs). [...]

Case Report: Clinical Usability of MyoMaps in Myocardial Infarction

These case reports show that current advances in T1 and T2 mapping and ECV quantification might have the potential to improve the diagnosis of cardiovascular disease, refine myocardial risk stratification and guide patient personalized therapeutic strategies. View/Download [...]

Cardiovascular Magnetic Resonance Teaching Network

The article introduces a novel teaching approach allowing time-effective teaching as well as an ongoing quality control. The aim is to enable CMR in all settings – hospitals of different sizes as well as in outpatient departments. [...]

Launch of the world’s first 7 T MR platform intended for clinical use (Siemens)

Erlangen, Germany, May 31, 2015 — Siemens announced at the Toronto ISMRM (International Society for Magnetic Resonance in Medicine) meeting the launch of the world’s first 7 T MR platform intended for clinical use. Important advances include a new, light, actively shielded magnet with zero helium boil-off and dual operating modes, enabling rapid switching between research […] [...]

CAIPIRINHA – Revisited

The development ofmulti coil receiver hardware as well as dedicated parallel acquisition techniques (PAT) and respective reconstruction methods allowed for a significant decrease of acquisition times in almost all clinical applications. This article provides a brief overview of 2D- and MS-CAIPIRINHA. [...]

Accelerated Diffusion Tensor Imaging of Skeletal Muscle Using Simultaneous Multi-Slice Acquisition

Simultaneous multi-slice acquisition with CAIPIRINHA reduces the scan time in diffusion-weighted MRI. In this article, early experience with this technique for accelerated DTI of skeletal muscle is shown. [...]

Simultaneous Multi-Slice (SMS) Imaging for Pre-Surgical BOLD fMRI and Diffusion Tractography: Case Illustrations

The presented case studies illustrate that SMS can increase the statistical confidence of fMRI and diffusion tractography results. These gains may be used to increase spatial image resolution and coverage, to improve spatial coregistration to high-resolution anatomical scans for intra-operative neuro-navigation, and / or to shorten acquisition times. [...]

Quiescent Interval Single-Shot (QISS) Lower Extremity MRA for the Diagnosis of Peripheral Artery Disease: Case Presentations

Case presentation of non-contrast QISS MRA providing high diagnostic accuracy for the detection of hemodynamically significant arterial stenosis of the lower extremities at both 1.5 and 3T. [...]

Point-of-Care MR Imaging and How We can Learn from Other Imaging Modalities. Thoughts on a Potential New Strategy

The article introduces point-of-care MRI, an extremely focused and goal-directed examinations strategy, that could reduce examination time and patient comfort. [...]

Simultaneous Multi-Slice (Slice Accelerated) Diffusion EPI: Early Experience for Brain Ischemia and Cervical Lymphadenopathy

In single shot EPI, the entirety of k-space is traversed after one shot (excitation). Readout-segmentation acquires k-space in multiple shots for reduced TE and encoding time. Real-time reacquisition of unusable shots is also supported. [...]

Clinical Case: 3 Tesla MR Neurography-Guided Posterior Femoral Cutaneous Nerve Block

The high SNR available at 3T provides the ability to perform high-resolution MR neurography-guided perineural injections for highly accurate visualization of small nerve as well as needle targeting and perineural injection. This case report demonstrates how this techniques facilitates accurate targeting of the PFCN.  Download/View PDF [...]

First Clinical Experiences with Simultaneous Multi-Slice Accelerated Diffusion-Weighted Imaging Throughout the Body

Dr. Valentin Tissot (CHRU, Brest, France) presents cases throughout the whole body that demonstrate that Simultaneous Multi-Slice (SMS) helps to accelerate diffusion-weighted imaging in almost all clinical cases where DWI is commonly applied. Robust results and good image quality can be achieved with an SMS factor of 2, which allows one to achieve near 2-fold acceleration. He also shows that ADC values are highly reproducible between the conventional and the accelerated technique. [...]

Iron Quantification with LiverLab

Liver iron content is an important clinical biomarker. Used with care, the R2c* values of the multi-echo Dixon VIBE in LiverLab allow estimating liver iron content. This article provides guidelines for the evaluation of liver iron. [...]

MR LiverLab

MR offers promising techniques for fat and iron evaluation in routine clinical liver diagnostics. This article shares the knowledge of implementing LiverLab, a comprehensive package which provides fat signal fraction (correlating with hepatic steatosis) and R2* of water (correlating with iron content). [...]

Case Series: Utilization of the Pediatric 16 Coil for 1.5T and 3T Systems

In this article we share some of our experiences over the last few years with MR upgrades. [...]

Long-term Experience with MR Upgrades

In this article we share some of our experiences over the last few years with MR upgrades. [...]

Rapid Estimation of Myelin for Diagnostic Imaging (REMyDI)

The article describes a new MRI myelin detection model to measure the presence of myelin by its effect on the surrounding cellular water, and discusses clinical applications of this technique. Download/View PDF [...]

fit-Upgrade: A Success Story

The fit-upgrade for 1.5 and 3T systems remains an economically attractive approach for an aged MR system. By improving system performance and workflow, the number of examinations can be increased, together with improved image quality, with little effort. Download/View PDF [...]

First Experiences with the Whole-Body Dot Engine

Whole-body MRI is beneficial in many clinical scenarios including bone marrow, infectious and rheumatic diseases. The Whole-Body Dot Engine provides fast and robust image quality across all patients, with fewer errors or need for repeated examinations. It ensures that all stations of a multi-station examination are performed with a consistent FOV and spatial resolution while […] [...]

Val M. Runge, MD – ASNR 2015 – Pearls and Pitfalls in Neuroradiology of Cerebrovascular Disease – The Essentials with MR and CT

This educational exhibit was presented at the ASNR 2015 meeting, with imaging performed on a 3 T Siemens Skyra MR system. The full reference for the exhibit is given below. Runge V, Smoker W, Valavanis A. Pearls and Pitfalls in Neuroradiology of Cerebrovascular Disease – The Essentials with MR and CT. ASNR 53rd Annual Meeting, […] [...]

Val M. Runge, MD – ASNR 2015 – Simultaneous Multi-Slice (Slice Accelerated) Diffusion EPI

This educational exhibit was presented at the ASNR 2015 meeting, with imaging performed on a 3 T Siemens Skyra MR system. The full reference for the exhibit is given below. Runge V, Richter J, Beck T, Piccirelli M, Valavanis A. Simultaneous Multi-Slice (Slice Accelerated) Diffusion EPI. ASNR 53rd Annual Meeting, April 25-30, 2015, Chicago, Illinois […] [...]

Val M. Runge, MD – Editorial – 50th anniversary issue of Investigative Radiology

ZURICH, May 12, 2015 — Val M. Runge, MD, editor-in-chief of Investigative Radiology, one of the world’s leading scientific journals in the field of imaging, previews in his editorial the upcoming anniversary issue of the journal. The 50th anniversary issue focuses on research (reflecting the very basis of the journal), specifically on the current top fields in clinical imaging, […] [...]

Val M. Runge, MD leads 50th anniversary issue of Investigative Radiology

ZURICH, April 6, 2015 /PRNewswire-iReach/ — Val M. Runge, MD, editor-in-chief of Investigative Radiology, one of the world’s leading scientific journals in the field of imaging, previews the upcoming anniversary issue of the journal. Scheduled to be published in September 2015, the issue includes 11 landmark articles, with the first already available on line (published ahead-of-print). (full […] [...]

Practical Considerations for the Evaluation of the Neuroforamina in Routine Spine Imaging at 3T. A Case Series

Pathologies of the neuroforamina are one of the most frequent indications for spine surgery. However, in standard MRI with axial and sagittal planes and relatively thick slices (>3 mm) the diagnostic information may be limited for proper evaluation of the nerve roots. Prof. Marc-André Weber et al. (University Hospital Heidelberg, Germany) share practical tips on […] [...]

Standardized Quality and Process Efficiency with High-Throughput MR Exams

Standardized Quality and Process Efficiency with High-Throughput MR Exams. MR 2015 Garmisch (Germany), 16th International MRI Symposium. January 30, 2015. [...]

Improving MR Joint Diagnostics with T1 Water Contrast Using a RESTORE Pulse

The article discusses technical considerations and various clinical applications of the DESS sequence. 3D DESS techniques have advantages in assessment of pediatric cartilage pathology including higher SNR, increased cartilage-to-fluid contrast and isotropic resolution, which helps to reduce partial volume effects. 3D DESS techniques are also of essential importance in the pediatric population due to the lack of ionizing radiation. [...]

Amide Proton Transfer MRI in Patients with High-Grade and Low-Grade Gliomas

This article shows that the non-invasive technique of Amide Proton Transfer (APT) MRI has the potential to improve the differentiation of high and low grade gliomas of the brain, further expanding the repertoire of molecular imaging techniques. [...]

Case Report: Assessment of Renal Allograft Function with DTI and Tractography

The article discusses technical considerations and various clinical applications of the DESS sequence. 3D DESS techniques have advantages in assessment of pediatric cartilage pathology including higher SNR, increased cartilage-to-fluid contrast and isotropic resolution, which helps to reduce partial volume effects. 3D DESS techniques are also of essential importance in the pediatric population due to the lack of ionizing radiation. [...]

3T MR Imaging of the Pediatric Cartilage Using 3D Dual Echo Steady State (DESS)

The article discusses technical considerations and various clinical applications of the DESS sequence. 3D DESS techniques have advantages in assessment of pediatric cartilage pathology including higher SNR, increased cartilage-to-fluid contrast and isotropic resolution, which helps to reduce partial volume effects. 3D DESS techniques are also of essential importance in the pediatric population due to the lack of ionizing radiation. [...]

‘White Dots’ on Cranial MRI: MS and Differential Diagnosis

The article discusses technical considerations and various clinical applications of the DESS sequence. 3D DESS techniques have advantages in assessment of pediatric cartilage pathology including higher SNR, increased cartilage-to-fluid contrast and isotropic resolution, which helps to reduce partial volume effects. 3D DESS techniques are also of essential importance in the pediatric population due to the lack of ionizing radiation. [...]

Neuroradiology – Where Quantitative Imaging Helps Making a Better Diagnosis

Neuroradiology – Where Quantitative Imaging Helps Making a Better Diagnosis. June 12, 2014. Annual Congress of the Swiss Society of Radiology, Montreux, Switzerland. [...]

Contrast Enhanced MRI

Contrast Enhanced MRI. Research Imaging Seminar. MD Anderson Center, June 21, 2012, Houston, Texas [...]

Gadolinium Contrast Agent Safety

Gadolinium Contrast Agent Safety. MR 2015 Garmisch (Germany), 16th International MRI Symposium. January 31, 2015 [...]

MAGNETOM Aera – Combining Throughput and Highest Quality MR Angiography in an Optimized Clinical Workflow

This paper shows how the simultaneous use of multipurpose loop coils in MRI allows high-resolution musculoskeletal studies with increased contrast and specificity for assessing muscles, tendons, ligaments, joints, and cartilage. Dr. Ferrer presents a number of different daily patient routine examinations, including specifically evaluation of the carpal bones, the thumb metacarpals, the metacarpals, the distal inter-phalangeal joints, the elbow and ankle. [...]

MRI Assessment of Articular Cartilage Repair

The evolution of sophisticated surgical repair procedures for the treatment of isolated, focal traumatic or degenerative cartialge lesions has created the need for accurate, non-invasive assessment of the repair tissue. MRI depicts well subchondral bone and bone marrow, allowing examination of repair tissue and its interface with parent cartilage and complications of repair surgeries such as graft hypertrophy and delamination. [...]

Clinical Application of Diffusion Tensor Imaging in Radiation Planning for Brain Tumors

The evolution of sophisticated surgical repair procedures for the treatment of isolated, focal traumatic or degenerative cartialge lesions has created the need for accurate, non-invasive assessment of the repair tissue. MRI depicts well subchondral bone and bone marrow, allowing examination of repair tissue and its interface with parent cartilage and complications of repair surgeries such as graft hypertrophy and delamination. [...]

Comprehensive MRI-Based Staging of Rectal Cancer. Beneficial Combination of Local High- Resolution Imaging and a Moving-Table Platform for Simultaneous Detection of Metastasis

The evolution of sophisticated surgical repair procedures for the treatment of isolated, focal traumatic or degenerative cartialge lesions has created the need for accurate, non-invasive assessment of the repair tissue. MRI depicts well subchondral bone and bone marrow, allowing examination of repair tissue and its interface with parent cartilage and complications of repair surgeries such as graft hypertrophy and delamination. [...]

MAGNETOM Aera – Combining Throughput and Highest Quality Spine Imaging in an Optimized Clinical Workflow

The term WARP summarizes methods to minimize the impact of metal implants on MR image quality. This article introduces different techniques such as high bandwidth, VAT and SEMAC. [...]

MSK Imaging Tips and Tricks

Mark Lourensz from the MRI Department at St. Vincent’s Hospital in Melbourne, Australia shares tips and tricks on a broad range of musculoskeletal topics extending from standard joint MRI to whole limb tumor evaluation. Some of these may be common sense, but it doesn’t hurt to revisit the basics occasionally. [...]

Job’s Syndrome

Contrast-enhanced MR imaging is a particularly sensitive method for detecting soft-tissue masses, providing as well precise localization and definition of extent. In his case report, G. Hadjidekov et al. (Sofia, Bulgaria) presents a rare immunodeficiency disorder known as Job’s syndrome. The case shows the usefulness of MRI to analyze skin disorders and deeper soft-tissue masses in various locations. [...]

Bone and Soft Tissue Tumor Imaging: An Overview

Tumor imaging can be daunting, given the high stakes involved with a missed diagnosis or mis-diagnosis resulting in unnecessary further investigations, biopsies or even surgeries. In their article Marcus Pianta, Mark Lourensz et al. (St. Vincent’s Hospital, Fitzroy, Australia) describe their routine imaging protocol targeted to bone and soft tissue lesions, describe reporting and what the referring physicians need to know. [...]

MR Neurography – Diagnostic Criteria to Determine Lesions of Peripheral Nerves

MR Neurography is an excellent technique for visualization and evaluation of peripheral nerve disorders. In their article Philipp Bäumer et al. (Heidelberg University Hospital, Heidelberg, Germany) show high resolution intra-neural fascicular detail in both normal and abnormal states and cover different aspects including clinical indications, protocols, pitfalls, and useful applications. [...]

Sinding-Larsen-Johansson Disease

An 11-year-old female patient presented with pain in the left knee during extension and flexion manoeuvres of the knee following horseback exercises. Based on physical examination, a partial rupture of the left patellar ligament was suspected. In his case report, Axel Goldmann, MD (Orthopedic Center, Erlangen, Germany) describes the MRI findings of rarely seen SLJ disease. [...]

Brain Perfusion; How & Why

Pathologic perfusion is sometimes the reason and often the consequence of brain pathologies. Evaluation of perfusion with dynamic susceptibility-weighted imaging is a well understood and established method to evaluate these changes. In this article, Binesh et al. (Cedars Sinai Medical Center, Los Angeles) show step-by-step how they apply this method and present four case reports illustrating the usefulness of perfusion imaging in clinical practice. [...]