Giant cell tumor


C D2


Clinical History: 40 year old man with left knee pain for three months

Diagnosis: Giant cell tumor involving the proximal tibia with intratumoral hemorrhage

MR Technique:

Knee imaging was performed on a 3T MR system (Skyra, Siemens). (A) Axial T1-weighted TSE (TR/TE 700/12ms) images and (B) axial T2-weighted TSE images with Dixon fat suppression (TR/TE 2600/85ms) were acquired along with (C) coronal and (D) sagittal STIR images (TR/TE 3000/39ms, TI 230ms).

Imaging Findings:

An intra-osseous mass involves the proximal tibia and demonstrates predominantly well-circumscribed margins. The tumor is low signal intensity on T1WI with markedly decreased signal intensity throughout the lesion on fat-suppressed T2WI and STIR images. Scattered cystic components with high signal intensity are seen adjacent to the lesion with extensive associated soft tissue edema. Areas of low signal intensity on both T1WI and T2WI suggest hemosiderin from intratumoral hemorrhage.