Glioblastoma, right parietal in location

A relatively well-defined enhancing mass lesion is seen, with prominent accompanying vasogenic edema. Despite the absence of gross central necrosis, the abnormal high signal intensity on FLAIR extends within the splenium of the corpus callosum, and extended (on images not presented) to the left as well. This finding is consistent with infiltration of the corpus callosum by a high-grade astrocytoma, raising the suspicion of a glioblastoma. rCBV is high, within the enhancing portion of the lesion, supporting this diagnosis. Proton spectroscopy is compatible with neoplasia, but otherwise of little value. Note the lactate peak, consistent with anaerobic metabolism (and seen in higher grade tumors). Although the enhancing portion of the lesion has high signal intensity on the DWI image, this proved to be T2 shine through, without accompanying restricted diffusion (the ADC map is not presented).

Glioblastoma, right parietal in location
Part of the on-line supplement to Neuroradiology – The Essentials with MR and CT (© 2015)