Investigative Radiology July 2020

Assessment of Low-Grade Focal Cartilage Lesions in the Knee With Sodium MRI at 7 T

Fritz Fig1b Objective: Several articles have investigated potential of sodium (23Na) magnetic resonance imaging (MRI) for the in vivo evaluation of cartilage health, but so far no study tested its feasibility for the evaluation of focal cartilage lesions of grade 1 or 2 as defined by the International Cartilage Repair Society. The aims of this study were to evaluate the ability of 23Na-MRI to differentiate between early focal lesions and normal-appearing cartilage, to evaluate within-subject reproducibility of 23Na-MRI, and to monitor longitudinal changes in participants with low-grade, focal chondral lesions.  View/Download


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