Multiple sclerosis, cervical and thoracic cord lesions

An enhancing cervical cord lesion is noted on sagittal and axial images, located at the C2 level, with an additional thoracic lesion (which did not enhance) depicted on a lower axial T2-weighted section. Neither lesion respects gray-white matter boundaries, as seen on the axial T2-weighted scans, a common finding for MR lesions of the cord. […] [...]

Multiple sclerosis

The axial FLAIR image reveals numerous punctate, predominantly discrete, small hyperintense foci in the supraventricular white matter. Cord lesions and characteristic callosal lesions on the sagittal FLAIR image confirm the diagnosis of multiple sclerosis, with the caveat that the lesion load is very high in this patient. A post-contrast T1-weighted axial scan reveals lesions without […] [...]

Multiple sclerosis, interval development of a new small callosal lesion on a 2-year follow-up exam

Multiple sclerosis, interval development of a new small callosal lesion on a 2-year follow-up exam. Multiple immediate periventricular small punctate high signal intensity plaques are noted on sagittal FLAIR scans, characteristic for MS. Also present are several plaques within the frontal and occipital white matter. Note the interval development of a small plaque with a […] [...]

Multiple sclerosis, visualization of plaques with differing MR techniques

As with most brain lesions, MS plaques demonstrate low signal intensity on T1- and high signal intensity on T2-weighted scans. Of note is that some MS plaques manifest low signal intensity on T1-weighted scans relative to normal appearing white matter, so called “Black Holes”. These are felt to represent areas of irreversible demyelination and axonal […] [...]