Nonsecretory Multiple Myeloma MRI Monitoring of Therapy Response

Multiple myeloma is a malignant hematologic disorder characterized by the infiltration of neoplastic plasma cells into bone marrow. Detection of medullary involvement is best accomplished with the aid of MRI. Visualization of myeloma burden at baseline and during therapy is beneficial for improved patient management and accurate prognostic evaluation. Therefore, whole-body imaging protocols are mandatory, especially for assessment of myeloma infiltration in all bone marrow cavities (medullary involvement) as well as for diagnosis of extramedullary involvement. [...]