Diffusion and perfusion MR parameters to assess preoperative short course radiotherapy response in locally advanced rectal cancer: a comparative explorative study among parameters derived from standardized index of shape DCE-MRI, intravoxel incoherent motion, and diffusion kurtosis imaging

To assess preoperative Short Course Radiotherapy (SCR) tumor response in locally advanced rectal cancer (LARC) by means of parameters derived from Standardized Index of Shape (SIS) dynamic contrast enhanced (DCE) MRI, Apparent Diffusion Coefficient (ADC), Intravoxel Incoherent Motion and Diffusion Kurtosis Imaging derived parameters by diffusion weighted (DW) MRI. [...]

Multiparametric MRI at 3 Tesla for Prediction of Treatment Response in Rectal Cancer

The article describes the successful integration of a multiparametric MRI technique to monitor response to treatment in patients with rectal cancer. A voxel-by-voxel multiparametric analysis strategy has been adopted and early results show this is important in quantitatively assessing heterogeneity within the entire tumor region, and the changes in response to CRT in rectal cancer. [...]